Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4810
Gene Symbol: NHS
NHS 		0.100 GeneticVariation disease GWASDB A genome-wide association study identifies susceptibility loci for Wilms tumor. 22544364 2012
Entrez Id: 6948
Gene Symbol: TCN2
TCN2 		0.100 GeneticVariation disease GWASDB A genome-wide association study identifies susceptibility loci for Wilms tumor. 22544364 2012
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9 		0.100 GeneticVariation disease GWASDB A genome-wide association study identifies susceptibility loci for Wilms tumor. 22544364 2012
Entrez Id: 1740
Gene Symbol: DLG2
DLG2 		0.100 GeneticVariation disease GWASDB A genome-wide association study identifies susceptibility loci for Wilms tumor. 22544364 2012
Entrez Id: 2719
Gene Symbol: GPC3
GPC3 		0.800 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 7490
Gene Symbol: WT1
WT1 		0.800 Biomarker disease GENOMICS_ENGLAND Genotype-phenotype associations in WT1 glomerulopathy. 24402088 2014
Entrez Id: 7490
Gene Symbol: WT1
WT1 		0.800 Biomarker disease GENOMICS_ENGLAND ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing. 23788249 2013
Entrez Id: 7490
Gene Symbol: WT1
WT1 		0.800 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.720 Biomarker disease GENOMICS_ENGLAND Consensus for genes to be included on cancer panel tests offered by UK genetics services: guidelines of the UK Cancer Genetics Group. 29661970 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.720 Biomarker disease GENOMICS_ENGLAND ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing. 23788249 2013
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.720 Biomarker disease GENOMICS_ENGLAND Clinical and molecular features associated with biallelic mutations in FANCD1/BRCA2. 16825431 2007
Entrez Id: 10155
Gene Symbol: TRIM28
TRIM28 		0.620 Biomarker disease GENOMICS_ENGLAND We recommend that all individuals with Wilms tumour should be offered genetic testing and particularly, those with epithelial Wilms tumour should be offered TRIM28 genetic testing. 30885698 2019
Entrez Id: 1028
Gene Symbol: CDKN1C
CDKN1C 		0.480 Biomarker disease GENOMICS_ENGLAND CDKN1C expression in Beckwith-Wiedemann syndrome patients with allele imbalance. 10424812 1999
Entrez Id: 7490
Gene Symbol: WT1
WT1 		0.800 GeneticVariation disease UNIPROT The detection of one nonsense point mutation and one missense WT1 gene point mutation adds to the accumulating evidence implicating this gene in a proportion of Wilms tumor patients. 1317572 1992
Entrez Id: 7490
Gene Symbol: WT1
WT1 		0.800 GeneticVariation disease UNIPROT Identification of constitutional WT1 mutations, in patients with isolated diffuse mesangial sclerosis, and analysis of genotype/phenotype correlations by use of a computerized mutation database. 9529364 1998
Entrez Id: 7490
Gene Symbol: WT1
WT1 		0.800 GeneticVariation disease UNIPROT Correlation of germ-line mutations and two-hit inactivation of the WT1 gene with Wilms tumors of stromal-predominant histology. 9108089 1997
Entrez Id: 7490
Gene Symbol: WT1
WT1 		0.800 GeneticVariation disease UNIPROT Twenty-four new cases of WT1 germline mutations and review of the literature: genotype/phenotype correlations for Wilms tumor development. 15150775 2004
Entrez Id: 10664
Gene Symbol: CTCF
CTCF 		0.340 GeneticVariation disease UNIPROT
Entrez Id: 7273
Gene Symbol: TTN
TTN 		0.300 GeneticVariation disease UNIPROT
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.510 Biomarker disease RGD By immunohistochemistry, however, VHL protein level was evidently reduced in six of the eight eosinophilic renal epithelial tumors and in all the ten nephroblastomas. 11880179 2002
Entrez Id: 5076
Gene Symbol: PAX2
PAX2 		0.300 Biomarker disease RGD A rodent model for Wilms tumors: embryonal kidney neoplasms induced by N-nitroso-N'-methylurea. 7937920 1994
Entrez Id: 655
Gene Symbol: BMP7
BMP7 		0.210 Biomarker disease RGD Deficient expression of mRNA for the putative inductive factor bone morphogenetic protein-7 in chemically initiated rat nephroblastomas. 9808158 1998
Entrez Id: 2719
Gene Symbol: GPC3
GPC3 		0.800 Biomarker disease ORPHANET These findings imply a possible role for GPC3 in Wilms' tumour development. 12085187 2002
Entrez Id: 2719
Gene Symbol: GPC3
GPC3 		0.800 Biomarker disease ORPHANET The GPC3 gene product in Wilms tumor was further evaluated by immunohistochemistry and quantified by an automated image analysis. 25366870 2015
Entrez Id: 7490
Gene Symbol: WT1
WT1 		0.800 SusceptibilityMutation disease ORPHANET